Chinese researchers report that insomnia may lead to abnormalities in the white matter of the brain, the tissue which carries information between the various parts of the organ. For the study, the researchers recruited 23 patients with primary insomnia and 30 healthy volunteers. The participants completed surveys that allowed investigators to evaluate their mental status and sleep patterns. Using an advanced MRI technique, the research team also looked at the pattern of water movement in white matter to identify any irregularities. They found that participants with insomnia had significantly reduced white matter integrity in several regions of the brain including the thalamus, which regulates consciousness, sleep, and alertness, as well as the corpus callosum, the area that connects the two halves of the brain. Researcher Dr. Shumei Li notes, “Our results can potentially provide the evidence about how the lack of sleep may lead to the impairment of white matter related to emotional or cognitive disorders.”
Radiology, April 2016