Among a group of 46 rheumatoid arthritis patients with knee pain, those treated with ten sessions of manual therapy (joint mobilization and post isometric relaxation) experienced a greater reduction in knee pain than participants who received a standard exercise intervention. The research team recommends further studies to determine the role of manual therapy techniques, such as those provided by doctors of chiropractic, in the management of rheumatoid arthritis patients with musculoskeletal pain. Evidence-Based Complementary Alternative Medicine, August 2020