Health Alert: Cancer and Aging

Why does our risk of developing cancer increase as we age? By the time we stop growing in our teens, we accumulate a large percentage of the mutations we will have during our lifetime. There’s a mismatch between the mutation curve and the cancer curve, meaning that if cancer is caused by reaching a tipping point of mutations, then we should see higher cancer rates in 20-year-olds, as this is when the mutation rate is highest. The body’s healthy cells function best in healthy, younger tissue; however, in older tissue, cancerous cells may adapt better in that environment than healthy cells and more easily propagate.
Oncogene, June 2012