Exercise: Eat Less, Move More, and Live Longer

In a study on dietary restriction (DR) involving fruit flies, the flies that were also physically active experienced longer lives. This study establishes a link between DR-mediated metabolic activity in muscle, increased movement and the benefits derived from restricting nutrients. Flies on DR who could not move or had inhibited fat metabolism in their muscle did not exhibit an extended lifespan. If this finding extends to humans, then simply restricting nutrients without physical activity may not increase longevity.
Cell Metabolism, July 2012